PILA PHARMA AB

Logotype for PILA PHARMA AB
Ticker/ISIN
PILA
SE0015988274
Marknad/Land
SE
Sweden

Senaste sammanfattade pressmeddelande från PILA PHARMA AB

PILA PHARMA AB is inviting investors to an online webinar on February 27, 2025, where CEO Gustav H. Gram will discuss the company's 2024 second half-year report and their TRPV1 antagonist for obesity and related disorders. The company, listed on Nasdaq First North Growth Market, is a Swedish biotech firm focusing on developing TRPV1 antagonists as treatments for type 2 diabetes, obesity, and other inflammatory diseases. Their lead compound, XEN-D0501, has shown promise in clinical trials for obesity and type 2 diabetes, and has been granted orphan drug designation for erythromelalgia. PILA PHARMA is also exploring its use for abdominal aorta aneurysm, with preclinical success in reducing aneurysm growth in mice. The company is preparing for further clinical trials to assess safety and efficacy in these conditions.
PILA PHARMA AB has announced the completion of a study by Professor Dick Wågsäter's Research Group at Uppsala University, which showed that their TRPV1 antagonist, XEN-D0501, significantly reduced the growth of Abdominal Aorta Aneurysm (AAA) in mice. This establishes a preclinical proof-of-concept for the drug's potential to reduce chronic inflammation leading to cardiovascular diseases, including aorta dilatation. The study revealed that XEN-D0501 decreased aorta dilatation by over 50% compared to placebo, nearly inhibiting aneurysm development in the model. The results await further validation before publication. PILA PHARMA focuses on developing TRPV1 antagonists for type 2 diabetes and other inflammatory diseases. XEN-D0501 has shown good safety profiles in previous trials and is being prepared for further clinical studies. The company also holds patents for using TRPV1 antagonists in treating obesity and diabetes. PILA PHARMA is based in Malmö, Sweden, and is listed on the Nasdaq First North Growth Market.
PILA PHARMA AB has appointed Hampus Darrell as its new Chief Financial Officer (CFO). Hampus brings extensive experience in accounting and financial management, having worked in various roles at KPMG and E.ON, and as CFO at Setterwalls Advokatbyrå. He holds a Master of Science in Business and Economics from Lund University and became a Swedish Certified Public Accountant in 2005. Hampus will join PILA PHARMA part-time from December 2024, succeeding Elna Lembrér Åström, who is retiring. PILA PHARMA, a Swedish biotech company, focuses on developing TRPV1 antagonists for treating type 2 diabetes and other inflammatory diseases. The company owns the development candidate XEN-D0501, which has shown promise in clinical trials. PILA PHARMA is working on projects related to type 2 diabetes, erythromelalgia, and abdominal aorta aneurism. The company also collaborates with Uppsala University to study the effects of XEN-D0501 on abdominal aorta aneurism growth in mice.
PILA PHARMA AB has announced the start of a study in collaboration with Professor Dick Wågsäter's research group at Uppsala University. The study aims to investigate the effects of PILA PHARMA's lead molecule, XEN-D0501, on the growth of Abdominal Aorta Aneurism (AAA) in mice. The hypothesis is that XEN-D0501 may reduce inflammation leading to cardiovascular diseases, potentially preventing AAA's progression. PILA PHARMA will co-sponsor the research, with the Research Group retaining publication rights after patenting. If successful, this study could lead to human trials. PILA PHARMA, a Swedish biotech company, focuses on developing TRPV1 antagonists for type 2 diabetes and other inflammatory diseases. XEN-D0501 has shown promise in previous trials for diabetes and obesity, and the company is planning further clinical trials to explore its potential benefits.
PILA PHARMA AB, a Swedish biotech company, invites investors to several upcoming Nordic events where CEO Gustav H. Gram will discuss the company's innovative treatment for metabolic disorders. The company focuses on developing TRPV1 antagonists, particularly XEN-D0501, for conditions like type 2 diabetes, obesity, and erythromelalgia. XEN-D0501 has shown promise in clinical trials, improving insulin response and reducing cardiovascular biomarkers. The company plans further trials to assess safety and efficacy. PILA PHARMA also explores treatments for erythromelalgia and abdominal aorta aneurism, collaborating on preclinical studies to investigate XEN-D0501's potential effects. Diabetes and obesity are highlighted as significant global health issues, with obesity linked to increased risk of type 2 diabetes and cardiovascular diseases. The company's shares are traded on Nasdaq First North Growth Market in Sweden.
PILA PHARMA AB (publ) announced that its Chairman of the Board, Dorte X. Gram, and CEO, Gustav H. Gram, have purchased additional shares in the company. Dorte X. Gram, along with Gustav H. Gram, acquired 20,000 shares through their family investment vehicle, Gram Equity Invest AB, at an average price of SEK 4.99. Dorte X. Gram's total holdings now amount to 5,215,086 shares. Separately, Gustav H. Gram privately acquired 11,072 shares on November 15 and 5,914 shares on November 18, at an average price of SEK 4.58, bringing his total holdings to 96,802 shares. Both leaders expressed confidence in the company's potential, particularly in developing TRPV1 antagonists for treating metabolic diseases such as obesity, diabetes, and cardiovascular disease. PILA PHARMA is a Swedish biotech company focusing on developing these antagonists as novel treatments for type 2 diabetes and other inflammatory diseases. The company owns the TRPV1 asset XEN-D0501, which has shown promise in clinical trials. PILA PHARMA is also involved in projects related to erythromelalgia and abdominal aorta aneurism, with ongoing research and development efforts.
PILA PHARMA AB (publ) invites viewers to watch or listen to a broadcast of "Millionærklubben," featuring CEO Gustav H. Gram. He will discuss the company's innovative pill treatment for diabetes, obesity, and other metabolic disorders. The episode is in Danish and will be available on PILA PHARMA's digital platforms. PILA PHARMA is a Swedish biotech firm focused on developing TRPV1 antagonists, particularly XEN-D0501, for treating type 2 diabetes and other conditions. The company has completed two phase 2a clinical trials showing XEN-D0501 is well tolerated and enhances insulin response. Future plans include further trials to assess the safety and efficacy of the drug. PILA PHARMA is also exploring treatments for erythromelalgia and abdominal aorta aneurism. The company collaborates with Uppsala University to study XEN-D0501's effects on aneurism growth in mice.
PILA PHARMA AB has announced the selection of Professor Mark Evans as the principal investigator and Cambridge University Hospital as the main clinical trial site for their study PP-CT03. The decision follows changes to the trial plan due to safety concerns with non-hospital sites. PILA PHARMA will seek scientific advice from the UK MHRA to enhance the study design for their TRPV1 antagonist, XEN-D0501, aimed at treating diabetes and obesity. The company aims to optimize study efficacy and regulatory approval chances. Despite potential delays, they expect to receive scientific feedback in early 2025. PILA PHARMA focuses on developing treatments for type 2 diabetes, obesity, erythromelalgia, and abdominal aorta aneurism. Their lead molecule, XEN-D0501, has shown promise in previous trials and is being further developed for its potential benefits in metabolic diseases.

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Press Release: CEO Gustav H. Gram increases holding in PILA PHARMA AB

Pila Pharma AB (publ) (FN STO: PILA) announced that CEO Gustav H. Gram has purchased an additional 29,375 shares at an average price of SEK 5.1768, increasing his total holdings to 74,816 shares. Gram expressed his commitment to the company and confidence in its progress, citing an upcoming value-driving trial. Pila Pharma is focused on developing TRPV1 antagonists, particularly XEN-D0501, for type 2 diabetes, obesity, and cardiovascular diseases. The company has completed two phase 2a clinical trials showing good tolerability and efficacy in type 2 diabetic patients. Pila Pharma also has projects targeting erythromelalgia and abdominal aorta aneurism. The company's shares are traded on Nasdaq First North Growth Market, Sweden.

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Press Release: PILA PHARMA INVITES TO INVESTOR Q&A & PRESENTATIONS

PILA PHARMA AB (publ) invites investors to participate in three upcoming online events where CEO Gustav H. Gram will discuss the company's Half-year report for 2024 and answer questions about their innovative pill treatment for obesity and diabetes. The events are scheduled as follows: 1. Stokk.io Online Webinar on Tuesday, August 27, 2024, at 12:00 CET 2. Aktiespararna Online Life Science Day on Wednesday, August 28, 2024, at 20:00 CET 3. Redeye Online Investor Event on Thursday, August 29, 2024, at 14:00 CET PILA PHARMA is a Swedish biotech company focused on developing TRPV1 antagonists for treating type 2 diabetes and other inflammatory diseases. Their lead candidate, XEN-D0501, has shown promise in clinical trials and has received orphan drug designation for erythromelalgia. The company is preparing for further trials to assess the safety and efficacy of XEN-D0501 in obese patients with type 2 diabetes. For more information and to sign up for the events, visit the provided links or the company's website. PILA PHARMA's share ticker PILA is traded on the Nasdaq First North Growth Market in Sweden.

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Press Release: PILA PHARMA'S BOARD OF DIRECTORS ANNOUNCES COMPLETION OF A FULLY SUBSCRIBED DIRECTED ISSUE OF APPROXIMATELY SEK 10 MILLION

Pila Pharma AB's Board of Directors, authorized by a general meeting, has decided to issue 3,333,334 new shares at SEK 3.00 per share, raising approximately SEK 10 million before transaction costs. The new shares, allocated to subscribers based on payment, will increase the share capital by SEK 142,520.48683 and dilute existing capital and voting rights by 12.29%. The offer targeted a limited number of current and new investors, with 19 identified contacts, resulting in 15 individual presubscriptions. The company aims to use the funds for a phase 2a clinical study of its TRPV1 antagonist, XEN-D0501, to assess its effect on body weight regulation in obese, diabetic patients. The legal advisor for the issue is MAQS Advokatbyrå, and the issuing agent is Nordic Issuing AB. The information is published in compliance with the EU Market Abuse Regulation. Pila Pharma, listed on Nasdaq First North Growth Market, focuses on developing treatments for type 2 diabetes, erythromelalgia, and abdominal aorta aneurism using TRPV1 antagonists.

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Press Release: PILA PHARMA INKS AGREEMENT WITH LINDUS HEALTH ABOUT NEXT CLINICAL TRIAL WITH SAFETY AND OBESITY READOUTS

PILA PHARMA AB has announced an agreement with UK-based clinical research organization Lindus Health to support the submission of a clinical trial application for PP-CT03, a phase 2a study targeting obese individuals with type-2 diabetes. Lindus Health, known for its expertise in metabolic health and technology-driven trial execution, will assist in compiling and submitting the application. The trial aims to determine the maximum tolerable dose of XEN-D0501, assess its safety and tolerability, and evaluate its effects on body weight over three months. Recruitment is expected to begin in early autumn, pending approval. CEO Gustav H. Gram expressed optimism about the collaboration, highlighting Lindus Health's innovative model. PILA PHARMA focuses on developing TRPV1 antagonists for type 2 diabetes and other inflammatory diseases, with XEN-D0501 as a key candidate. The company also works on projects related to erythromelalgia and abdominal aorta aneurism. Lindus Health specializes in running efficient clinical trials and has conducted over 90 studies across various conditions.

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Press Release: PILA PHARMA'S BOARD OF DIRECTORS HAS RESOLVED TO CARRY OUT A DIRECTED ISSUE OF SHARES OF APPROXIMATELY SEK 10.0 MILLION

The Board of Directors of Pila Pharma AB has decided to issue up to 3,333,334 new shares at a subscription price of SEK 3.00 per share, potentially raising approximately SEK 10.0 million before transaction costs. This decision, authorized by a general meeting on April 18, 2024, deviates from shareholders' preferential rights and targets a limited number of current shareholders and new investors. The subscription period ends on July 23, 2024, but may be extended by the board. The funds will support the company's expansion and a clinical trial application, necessitated by recent trial design changes to include more participants. The transaction could cause a dilution effect of approximately 12.29% for non-participating shareholders. The subscription price was set based on a 30% discount on the Volume-Weighted Average Price (VWAP) from June 17 to July 5, 2024. The company aims to demonstrate sufficient funds for an ethics committee to approve the clinical trial, which could potentially enhance shareholder value. The legal advisor for the transaction is MAQS Advokatbyrå, and Nordic Issuing AB will act as the issuing agent.

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Press Release: Clarification: PILA PHARMA SPONSORS INTERNATIONAL DIABETES & NUTRITION CONFERENCE

PILA PHARMA announced its participation and co-sponsorship of the 41st International Symposium on Diabetes and Nutrition in Uppsala, Sweden from June 27-30. The company aims to spread awareness about using TRPV-1 antagonists for treating diabetes and other metabolic conditions. Dr. Dorte X. Gram, CSO and Founder, will present on targeting the TRPV1 receptor. PILA PHARMA is a Swedish biotech company focusing on developing TRPV1 antagonists, particularly XEN-D0501, for type 2 diabetes, obesity, and other conditions. They have completed two phase 2a trials showing XEN-D0501's safety and efficacy. The company is preparing for further clinical trials to determine the maximal tolerable dose in overweight or obese individuals with type 2 diabetes. PILA PHARMA also focuses on erythromelalgia and abdominal aorta aneurism research.

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Press Release: PILA PHARMA SPONSORS INTERNATIONAL DIABETES & NUTRITION CONFERENCE

The conference in Uppsala, Sweden, from June 27-30, will feature PILA PHARMA, invited by Professor Ulf Risérus of Uppsala University, a prominent expert in diabetes, nutrition, and obesity science. The event will gather international experts on these topics, with PILA PHARMA sponsoring SEK 50,000. Dr. Dorte X. Gram, CSO and Founder of PILA PHARMA, will present on using TRPV-1 antagonists to treat diabetes and other metabolic conditions. PILA PHARMA, based in Malmö, Sweden, focuses on developing TRPV1 antagonists as treatments for type 2 diabetes and other inflammatory diseases. They own the development candidate XEN-D0501, which has shown promise in clinical trials for diabetes and other conditions. The company also holds patents and aims to submit further patents related to TRPV1 antagonists. XEN-D0501 is a synthetic TRPV1 antagonist with applications in pain and inflammatory diseases, including diabetes. It has demonstrated good safety and efficacy in clinical trials, with plans for further studies to identify the maximum tolerable dose in overweight or obese type 2 diabetes patients. Diabetes and obesity are global health challenges, with significant unmet needs in treatment. Obesity often precedes type 2 diabetes and increases the risk of cardiovascular diseases. Advances in anti-obesity drugs have shown benefits in quality of life and longevity. Erythromelalgia is a rare disease causing pain and redness in extremities, with PILA PHARMA planning a proof-of-concept study on XEN-D0501's effects on this condition. Abdominal Aorta Aneurism is a cardiovascular disease with no current preventive treatments. PILA PHARMA is collaborating on research to investigate XEN-D0501's impact on the condition's growth in mice.

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Press Release: PILA PHARMA PRESENTS TOMORROW AT "AKTIESPARARNA"

PILA PHARMA AB (publ) (FN STO: PILA) will present at the Aktiespararna's "Store Aktiedagarna" event on Wednesday, June 12, 2024, at 08:00 CET. The presentation will take place in Stockholm, Sweden, and will be livestreamed. CEO Gustav H. Gram will discuss the company's latest developments and its innovative oral treatment for diabetes. The event will be in English and include a Q&A session. Pila Pharma is a Swedish biotech company focused on developing TRPV1 antagonists for type 2 diabetes and other inflammatory diseases. The company owns the development candidate XEN-D0501 and has completed two phase 2a clinical trials showing it is well tolerated by type 2 diabetic patients. Pila Pharma aims to further study XEN-D0501's effects on diabetes, obesity, erythromelalgia, and abdominal aorta aneurism. For more information, contact CEO Gustav H. Gram at ghg@pilapharma.com or visit the company's website. Pila Pharma's shares trade on Nasdaq First North Growth Market, Sweden.

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Press Release: PILA PHARMA PRESENTS TODAY AT REDEYE THEME: DIABETES

PILA PHARMA AB kommer att presentera på Redeye Theme: Diabetes idag, torsdag 23 maj 2024 kl 09:30 CEST. Presentationen kommer att hållas i Redeye's studio i Stockholm och kommer även att livestreamas. Intresserade parter och investerare är inbjudna att följa evenemanget och ställa frågor. VD Gustav H. Gram kommer att diskutera PILA Pharmas position inom diabetesområdet och hur deras innovativa orala behandling kan spela en roll i framtida behandling av diabetes och dess associerade sjukdomar. Det kommer även att vara en frågestund där frågor från Redeye-analytiker Filip Einarsson kommer att besvaras. PILA PHARMA är ett svenskt biotechföretag baserat i Malmö. Företaget äger en TRPV1-tillgång med data och kemiska enheter, inklusive utvecklingskandidaten XEN-D0501. De äger också användningspatent som täcker användningen av TRPV1-antagonister som behandling av fetma och diabetes och avser att lämna in ytterligare patent. Företagets aktier, PILA, handlas på Nasdaq First North Growth Market, Sverige. XEN-D0501 är en selektiv, syntetisk potent liten molekyl TRPV1-antagonist som licensierades in 2016. PILA Pharma har hittills slutfört två fas 2a kliniska prövningar (PP-CT01 och PP-CT02) som båda visade att XEN-D0501 tolereras väl av typ 2-diabetespatienter. Dessutom visade PP-CT02 att XEN-D0501 förbättrade den endogena insulinresponsen till oral glukos. Diabetes är en global pandemi med en förbluffande uppskattad förekomst av mer än 537 miljoner människor som lever med diabetes, motsvarande cirka 8-10% av den globala vuxna befolkningen. Trots nyligen terapeutiska framsteg finns det stora och växande ouppfyllda behov både från effektivitet, säkerhet och tillgänglighet.

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Press Release: CEO Gustav H. Gram increases holding in Pila Pharma AB

The newly appointed CEO of Pila Pharma AB, Gustav H. Gram, has bought additional shares in the company. The purchases were made in two parts, on May 10th and May 13th, totalling 22,209 shares. Gram now holds 45,441 shares in Pila Pharma AB. The company is focused on developing TRPV1 antagonists, a potential treatment for type 2 diabetes, erythromelalgia, and abdominal aorta aneurism. The company's drug candidate, XEN-D0501, has shown positive results in phase 2a clinical trials and is being prepared for further testing.

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